Plant Toxins:

The first 3500 years of aspirin history from its roots – A concise summary

“Green Smoothie Cleanse” Causing Acute Oxalate Nephropathy

Potato glycoalkaloids adversely affect intestinal permeability and aggravate inflammatory bowel disease

Effect of solanine on the membrane potential of mitochondria in HepG2 cells and [Ca2+]i in the cells

Effect of gliadin on permeability of intestinal biopsy explants from celiac disease patients and patients with non-celiac gluten sensitivity

Risks and Safety of Polyphenol Consumption

Comprehensive Natural Products II: 4.16.3.1.8 Solanine

Why Do Plants Make Drugs for Humans?

Horrific Tales of Potatoes That Caused Mass Sickness and Even Death

99.99% of pesticides are naturally occurring chemicals that plants make to defend themselves

Curcumin causes DNA damage and affects associated protein expression in HeLa human cervical cancer cells

Curcumin Triggers DNA Damage and Inhibits Expression of DNA Repair Proteins in Human Lung Cancer Cells

Glucosinolates (Goitrogenic Glycosides)

Pharmacology, Toxicology, and Pharmaceutical Science: Solanine

Nutrition and Metabolic Health

For 2 million years, humans ate meat and little else — study

Protein and amino acid requirements in human nutrition

Prevalence of Optimal Metabolic Health in American Adults: National Health and Nutrition Examination
Survey 2009–2016

Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012

Nutritional importance of animal source foods

Intestinal Lipid–derived Signals that Sense Dietary Fat

Sacred Cow Book by Diana Rodgers and Robb Wolf

American Heart Association: What is Metabolic Health

Dietary Carbohydrate Restriction Improves Metabolic Syndrome Independent of Weight Loss

Only 12 percent of American adults are metabolically healthy

Is Alzheimer’s disease related to metabolic syndrome? A Wnt signaling conundrum

The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia

Insulin Resistance & Prediabetes | NIDDK

Prevalence of and Trends in Diabetes Among Adults in the United States, 1988-2012

New Study of Protein Powders from Clean Label Project Finds Elevated Levels of Heavy Metals and BPA in 53 Leading Brands

CDC National Center for Health Statistics

NIH study shows how insulin stimulates fat cells to take in glucose

Physiologic Effects of Insulin 

Wheat and Gluten

The opioid effects of gluten exorphins: asymptomatic celiac disease

Markers of gluten sensitivity and celiac disease in recent-onset psychosis and multi-episode schizophrenia

Markers of gluten sensitivity in acute mania: a longitudinal study

International table of glycemic index and glycemic load values: 2002

Celiac Disease Facts and Figures 

Prolactin Release Is Enhanced in Proportion to Excess Visceral Fat in Obese Women

The Neuropathology of Gluten-Related Neurological Disorders: A Systematic Review

Dietary Advanced Glycation End-products (AGE) and Risk of Breast Cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO)

Estrogen Metabolism in Abdominal Subcutaneous and Visceral Adipose Tissue in Postmenopausal Women

Gluten in wheat: What has changed during 120 years of breeding?

Advanced Glycation End Products and Diabetic Complications

Neurologic and Psychiatric Manifestations of Celiac Disease and Gluten Sensitivity

Markers of gluten sensitivity and celiac disease in bipolar disorder

Non-celiac gluten sensitivity triggers gut dysbiosis, neuroinflammation, gut-brain axis dysfunction, and vulnerability for dementia

Adiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial Dysfunction

Rice-Induced Anaphylaxis: IgE-Mediated Allergy against a 56-kDa Glycoprotein

Coeliac disease and schizophrenia: population based case control study with linkage of Danish national registers

Is schizophrenia rare if grain is rare?

MIF-like sequences in milk and wheat proteins

Celiac disease and alopecia areata: report of a new association

Food Addiction:

Food addiction: A common neurobiological mechanism with drug abuse

Images of desire: food-craving activation during fMRI

Intense Sweetness Surpasses Cocaine Reward

Evidence for sugar addiction: Behavioral and neurochemical effects of intermittent, excessive sugar intake

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) from the American Psychiatric Association

DSM 5 Criteria for Substance Use Disorders

Smithsonian National Museum of American History: Snack Nation

 The Extraordinary Science of Junk Food

Swallow This: Serving Up the Food Industry’s Darkest Secrets 

Food Cravings Engineered By Industry

Gut Health:

Intrinsic Defense Mechanisms of the Intestinal Epithelium

Influence of gut microbiota on neuropsychiatric disorders

60 Minutes: Do probiotics actually do anything?

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

Is high diversity always a good thing?

Effect of dietary additives on intestinal permeability in both Drosophila and a human cell co-culture

Keeping gut lining at bay: Impact of emulsifiers

NIH Digestive Diseases Statistics for the United States

Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut

Allergy and the gastrointestinal system

Direct impact of commonly used dietary emulsifiers on human gut microbiota

Food additives: Assessing the impact of exposure to permitted emulsifiers on bowel and metabolic health

Burden of Gastrointestinal Symptoms in the United States: Results of a Nationally Representative Survey of Over 71,000 Americans

Artificial sweetener saccharin disrupts intestinal epithelial cells’ barrier function in vitro

Intestinal dysbiosis and permeability: the yin and yang in alcohol dependence and alcoholic liver disease

Review of harmful gastrointestinal effects of carrageenan in animal experiments

Crohn’s Disease Exclusion Diet Plus Partial Enteral Nutrition Induces Sustained Remission in a Randomized Controlled Trial

Environment:

UC Davis: Why Methane from Cattle Warms the Climate Differently Than CO2 from Fossil Fuels 

Soil Carbon Storage by Todd A. Ontl (Department of Natural Resource Ecology and Management, Iowa State University, Ames, IA) & Lisa A. Schulte (Department of Natural Resource Ecology and Management, Iowa State University, Ames, IA)

Environmental Defense Fund: Global Risk Assessment of High Nitrous Oxide Emissions from Rice Production 

Microsoft buys carbon credits from NSW cattle operation

Can Cows Help Mitigate Climate Change? Yes they can

United Nations Convention to Combat Desertification

Land Degradation – FAO

Cows, and farmers, are part of the solution to climate change by Ph.D Frank Mitloehner 

Only 60 Years of Farming Left If Soil Degradation Continues

EPA Sources of Greenhouse Gas Emissions

Sacred Cow by Diana Rodgers and Robb Wolf

The Vegetarian Myth by Lierre Keith

Greenhouse Gas Emissions from Soils – A Review

What Causes Ocean Dead Zones?

What is regenerative agriculture?

The Green, Blue, and Grey Water Footprint of Farm Animals and Animal Products 

Land Regeneration – Building Soil with Animal Impact: White Oak Pastures 

Yes, eating meat affects the environment, but cows are not killing the climate

Livestock and the Environment. Meeting the Challenge from the FAO 

Livestock: On our plates or eating at our table? A new analysis of the feed/food debate 

CDC Adult Obesity Facts

Meat Consumption Does Not Explain Differences In Household Food Carbon Footprints In Japan

The Environmental Impact of Dialysis vs Transplantation

UC Davis: The Biogenic Carbon Cycle and Cattle

Joint FAO/IAEA Report: Belching Ruminants, a minor player in atmospheric methane 

How Fertilizers Harm Earth

Reuters: Millions of Abandoned Oil Wells are Leaking Methane, a Climate Menace 

Could our farms become the world’s great untapped carbon sink? 

White Oak Pastures Study

The “Meat Causes Cancer” Myth

Carcinogenicity of consumption of red and processed meat

Unprocessed Red Meat and Processed Meat Consumption

Associations Between Unprocessed Red Meat and Processed Meat With Risk of Recurrence and Mortality in Patients With Stage III Colon Cancer

Cancer incidence in vegetarians: results from the European Prospective Investigation into Cancer and Nutrition (EPIC-Oxford)

Study: Red and processed meats don’t raise risk for death, recurrence in colon cancer

Meat intake and cause-specific mortality

Lifetime Risk of Developing or Dying From Cancer

WHO report says eating processed meat is carcinogenic: Understanding the findings

Low-Fat Dietary Pattern and Risk of Cardiovascular Disease

Dietary risk factors for colon cancer in a low-risk population

What Are the Risk Factors for Lung Cancer?

Peak Human Podcast Episode 24 with Dr. David Klurfeld 

Why is the World Health Organisation Anti-Meat

Food sources of nitrates and nitrites

Nitrates/Nitrites in Food—Risk for Nitrosative Stress and Benefits

A survey of nitrate and nitrite concentrations in conventional and organic-labeled raw vegetables at retail

Cured Meat Flavor and the Role of Nitrite in its Development

Evaluation of nitrate and nitrite contents in pickled fruit and vegetable products

IFT: Are Nitrates and Nitrites Misunderstood?

Nitrates in Processed Meats: What’s the Risk?

Bias and Agenda in Dietary Guidelines

Death by Food Pyramid by Denise Minger

The Big Fat Surprise by Nina Teicholz

Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)

Scientific American: Records Found in Dusty Basement Undermine Decades of Dietary Advice

Saturated Fat in Meat is not associated with Cardiovascular Disease – How to make it look like it is

Rethinking Dietary Saturated Fat by Eric Westman

Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis

The New York Times: How the Sugar Industry Shifted Blame to Fat 

Animal Fats are Superior to Plant Fats, and Seed Oils Toxic

Role of Physiological Levels of 4-Hydroxynonenal on Adipocyte Biology: Implications for Obesity and Metabolic Syndrome

Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance

Inhibition of nuclear T3 binding by fatty acids

Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis 

Induction of mitochondrial nitrative damage and cardiac dysfunction by chronic provision of dietary omega-6 polyunsaturated fatty acids

Free radicals, antioxidants and functional foods: Impact on human health 

Soybean Oil Is More Obesogenic and Diabetogenic than Coconut Oil and Fructose in Mouse: Potential Role for the Liver

An oxidized metabolite of linoleic acid stimulates corticosterone production by rat adrenal cells

Toxicity of Air-Oxidized Soybean Oil

Studies to Determine the Nature of the Damage to the Nutritive Value of Some Vegetable Oils from Heat Treatment: IV. Ethyl Esters of Heat-Polymerized Linseed, Soybean and Sunflower Seed Oils

Exacerbation of heart and liver lesions in rats by feeding of various mildly oxidized fats

Household Use of Solid Fuels and High-temperature Frying

Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers

Current Evidence Linking Polyunsaturated Fatty Acids with Cancer Risk and Progression

The Influence of Dietary Fatty Acids on Immune Responses

A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans

Dietary linoleic acid intake and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials

Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity 

Omega-6 vegetable oils as a driver of coronary heart disease: the oxidized linoleic acid hypothesis

The Saturated Fat–Unsaturated Oil Dilemma: Relations of Dietary Fatty Acids and Serum Cholesterol, Atherosclerosis, Inflammation, Cancer, and All-Cause Mortality

The Brain Needs Animal Fat 

AJCN Publishes A New PUFA Study That Should Make Us Long For the Old Days

The Hateful Eight with Dr. Cate Shanahan

The Weston A. Price Foundation: Good Fats, Bad Fats: Separating Fact from Fiction

The Big Fat Surprise by Nina Teicholz

Sugar Industry and Coronary Heart Disease Research: A Historical Analysis of Internal Industry Documents

Harvard School of Public Health: Low-fat diet not most effective in long-term weight loss

MPKB Autoimmunity Research Foundation: Immune Suppression

Saturated fatty acids suppress adrenocorticotropic hormone (ACTH) release from rat anterior pituitary cells in vitro

First report on quality and purity evaluations of avocado oil sold in the US

Report: Most Imported Extra Virgin Olive Oils Aren’t Extra Virgin

UC Davis: Most imported olive oils don’t match ‘extra virgin’ claims, study finds

Slippery Business: The trade in adulterated olive oil

‘Four out of five’ bottles of Italian olive oil debased

Saturated Fats and the Lungs

Diet High in Soybean Oil Increases Susceptibility to Colitis in Mice

Oxidized Linoleic Acid Interacts with Gut Microbiota to Promote Colitis and Colorectal Cancer